Vitamin D3 + K2 with BioPerineĀ® | Bone & Cardiovascular Support | 60 Capsules
Why D3 and K2 work better together
Vitamin D3 and Vitamin K2 are fat-soluble nutrients that work synergistically to support calcium metabolism, bone density, and vascular health. Taking them together is considered more effective than either alone, because D3 increases calcium absorption while K2 helps direct calcium toward the bones and away from soft tissues.
Vitamin D3 (Cholecalciferol)
Vitamin D3 is the body's preferred form of vitamin D. It supports:
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Calcium and phosphorus absorption from the gut, which are essential for building and maintaining strong bones
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Normal immune system function ā clinical studies have associated adequate vitamin D levels with improved immune outcomes and shorter recovery times from illness
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Muscle function and mood regulation, according to observational and mechanistic research
Vitamin K2 (MK-7 / Menaquinone)
MK-7 is the long-acting, most bioavailable form of Vitamin K2. Research suggests it may support:
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Bone mineral density by activating osteocalcin, a protein that binds calcium into the bone matrix
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Cardiovascular health by activating Matrix Gla Protein (MGP), which may help inhibit arterial calcification ā a recognized cardiovascular risk factor
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Normal blood clotting function through the activation of clotting-related proteins
Note: Vitamin K2 supports normal, healthy blood clotting as part of its physiological role. It is distinct from anticoagulant therapy. Individuals on blood-thinning medications should consult their physician before use.
BioPerineĀ® Black Pepper Extract
BioPerineĀ® (standardized piperine from Piper nigrum) is a patented ingredient clinically shown to enhance the bioavailability of fat-soluble nutrients, including vitamins D and K, by up to 20x in some studies. Its inclusion helps ensure you absorb more of what's in each capsule.
What the research says
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A review of vitamin K2 research found positive associations with bone health outcomes, including osteoporosis, as well as potential benefits in cardiovascular-related calcium disorders (Maresz, 2015, Integrated Medicine).
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Vitamin D3 supplementation has been associated with significantly improved vitamin D status and a reduced duration of hospitalization in patients with vitamin D deficiency (Annweiler et al., clinical data).
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A clinical study in pediatric hemodialysis patients found that combined vitamin K2 and native vitamin D supplementation showed beneficial effects on calcification-regulating proteins (Shroff et al., Pediatric Nephrology).
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
| Product Details |
| Form |
Vegetable capsule (cellulose) |
| Servings |
30 (60 capsules) |
| Manufactured in |
USA |
| Net weight |
0.25 lb (113 g) |
Full Ingredient List: Calcium (as Calcium Carbonate), Vitamin D3 (Cholecalciferol), Vitamin K2 MK-7 (as Menaquinone), BioPerineĀ® Black Pepper Fruit Extract, Cellulose (vegetable capsule)
Suggested Use
Take one (1) capsule twice daily as a dietary supplement. For best absorption, take 20ā30 minutes before a meal with a fat-containing food, or as directed by your healthcare provider.
Cautions & Warnings
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Do not exceed the recommended dose.
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Consult a physician before use if you are pregnant, nursing, under 18, or have a known medical condition ā particularly if you take blood-thinning medications (e.g., warfarin), as vitamin K2 may interact with anticoagulant therapy.
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Keep out of reach of children.
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Do not use if the safety seal is damaged or missing.
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Store in a cool, dry place away from direct sunlight and moisture.
Frequently Asked Questions (AEO-optimized)
What does Vitamin D3 with K2 do? This combination supports calcium absorption (D3), directs calcium into bones rather than arteries (K2), and may promote bone density and vascular health over time.
What is MK-7 vitamin K2? MK-7 (menaquinone-7) is a long-chain, highly bioavailable form of vitamin K2 that remains active in the body longer than shorter-chain forms like MK-4.
What is BioPerineĀ® used for? BioPerineĀ® is a patented black pepper extract that enhances the absorption of fat-soluble nutrients, improving the effectiveness of each dose.
Is this product vegetarian? Yes. The capsule shell is made from cellulose, a plant-derived material. No gelatin is used.
Who should not take D3 + K2? Individuals on anticoagulant medications, pregnant or nursing women, and those under 18 should consult a physician before use.
Science behind this product
Use these facts to educate your customers and promote your products.
Vitamin K2 for Calcium-related Disorders
Data indicates that vitamin K2 positively impacted osteoporosis, cardiovascular disease, parathyroid disorders, cerebral palsy, and sperm motility.
Source
Vitamin D3 for Immunity
Vitamin D3 therapy led to a significant increase in Vitamin D3; the patients recovered from the hospital five days sooner than on average.
Source
Vitamin K2 for Vascular Calcification
Vitamin K2 and native vitamin D showed a beneficial effect on calcification regulators in pediatric hemodialysis patients.
Source
