Three Kasivit products sold together: Probiotic 40 Billion with Prebiotics, Digestive Enzyme Pro Blend and L-Glutamine Powder.
These are three separate products that are also sold individually. The combination has not been studied, and none of the products is a treatment for irritable bowel syndrome, "leaky gut", bloating or any other condition. Two of the products contain live bacteria. If you take any medicine, including a GLP-1 medicine or antibiotics, ask your prescriber or pharmacist before use. See a doctor for persistent digestive symptoms.
Probiotic 40 Billion with Prebiotics — per the confirmed label, a 2-capsule serving provides 40 billion CFU in a proprietary blend of four strains (Lactobacillus acidophilus La-14, Bifidobacterium lactis Bl-04, Lactobacillus plantarum Lp-115 and Lactobacillus paracasei Lpc-37) with the manufacturer's MAKTREK delivery system, plus fructooligosaccharide (24 mg) and a marine polysaccharide complex (60 mg). Probiotic effects are strain-specific. In a meta-analysis of 53 trials in adults with irritable bowel syndrome, particular probiotic combinations or strains appeared to help global symptoms and abdominal pain, but definitive conclusions could not be drawn (Ford 2018), and in a meta-analysis of 63 trials probiotic use was associated with a lower risk of antibiotic-associated diarrhea, with large differences between trials (Hempel 2012). No study of this product is cited.*
Digestive Enzyme Pro Blend — per the supplier, a capsule contains the Makzyme-Pro blend (fungal protease with Lactobacillus acidophilus, L. casei and L. plantarum), bromelain, papain, fungal lipase, fungal lactase and alpha galactosidase; the amount of each enzyme and the bacterial count are not stated. Prescription pancreatic enzymes are an established therapy in some digestive disorders (Ianiro 2016), but for over-the-counter blends the evidence is limited: in a pilot crossover trial in 20 adults with irritable bowel syndrome, alpha-galactosidase was not better than placebo for symptoms after meals high in oligosaccharides (Böhn 2021). No study of this product is cited.*
Kasivit L-Glutamine Powder — unflavored powder; per the supplier, each scoop (3.3 g) provides 3.15 g of L-glutamine. In an 8-week trial in 106 adults with post-infectious, diarrhea-predominant irritable bowel syndrome and increased intestinal permeability, 15 g of glutamine a day improved symptom scores and permeability compared with placebo (Zhou 2019), while a meta-analysis of 10 placebo-controlled trials in other groups found no significant overall effect on intestinal permeability (Abbasi 2024). One scoop provides far less than 15 g. "Leaky gut" is not an accepted medical diagnosis (Lacy 2024).*
Each product is also sold individually on its own page.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.