Kasivit High Potency Probiotic with Prebiotics Capsules 60ct
✓ Third-Party Tested✓ GMP-Certified Facility✓ FDA-Registered Facility✓ Manufactured in the USA using globally sourced ingredients✓ Gluten-Free✓ Lactose-Free✓ Allergen-Free✓ Sugar-Free
Kasivit

Kasivit High Potency Probiotic with Prebiotics Capsules 60ct

Multi-strain probiotic with 40 billion CFU per 2-capsule serving from 4 strains (La-14, Bl-04, Lp-115, Lpc-37), plus fructooligosaccharide prebiotic fiber and a marine polysaccharide complex.

💊Take 2 capsules daily (1 during the day and 1 in the evening). Do not exceed 2 capsules per day.
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🇺🇸 Manufactured in the USA using globally sourced ingredients
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🔬 Evidence-Rated

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Bronze Evidence Rating

Emerging research tier · Limited human research exists on the main ingredient. This describes published research, not this product.

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This rating describes how much published human research we found on the main ingredient. It is not a test or review of this product, it does not mean the product treats or prevents any condition, and it is not medical advice. View the Evidence Standard →

Why It Works

Key Benefits

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40 Billion CFU per Serving
According to the Supplement Facts panel, one serving (2 capsules) provides 40 billion CFU from four strains in a proprietary blend: Lactobacillus acidophilus La-14, Bifidobacterium lactis Bl-04, Lactobacillus plantarum Lp-115 and Lactobacillus paracasei Lpc-37. CFU is a count of live organisms and does not by itself show an effect; effects depend on the strain. The label does not state a CFU count at the end of shelf life.
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Four Strains in One Formula
A review of probiotic mixtures found that in 12 of 16 studies comparing a mixture with its separate strains, the mixture was more effective, but it is unclear whether this reflects synergy or a higher dose. The four strains named on the label have been tested together in a laboratory simulation of digestion, not in people. Effects of this exact blend on health outcomes have not been shown.
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Prebiotic Fiber Included
Each serving contains 24 mg of fructooligosaccharide (FOS), a prebiotic fiber that gut bacteria can ferment, and 60 mg of a complex marine polysaccharide. A review of rapidly fermentable fibers such as FOS found they may suit people who tolerate them, but can cause gas or bloating in susceptible people.
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Research on Antibiotic-Associated Diarrhea
A 2012 meta-analysis of 63 trials found probiotic use was associated with a lower risk of antibiotic-associated diarrhea (relative risk 0.58), but results varied and a 2025 Cochrane review rated the certainty as low. In a study in mice and human volunteers, probiotics taken after antibiotics were associated with slower, incomplete gut microbiome recovery. This product was not tested for this purpose; ask your prescriber or pharmacist before combining it with antibiotics.
✅This product is for you if…
You want a multi-strain probiotic supplement with 40 billion CFU per 2-capsule serving
You want a probiotic that also contains a prebiotic fiber (fructooligosaccharide)
You have checked with your doctor or pharmacist if you take regular medicines or have a medical condition
⚠️Consult your healthcare provider if…
You are pregnant or breastfeeding. Ask your doctor or pharmacist first
You have a weakened immune system (for example organ transplant or chemotherapy). Ask your doctor first
You have a central venous catheter or other indwelling line, or you are seriously ill or in intensive care. Rare bloodstream infections linked to probiotic bacteria have been reported. Ask your doctor first
You have severe acute pancreatitis or another serious pancreas condition. A trial of a multispecies probiotic in predicted severe acute pancreatitis found higher mortality. Ask your doctor first
You have SIBO or other ongoing digestive symptoms, or take prescription medicines (including GLP-1 medicines). Ask your prescriber or pharmacist first
Premature infants and newborns. This product is not intended for them. Ask a clinician before giving it to children
Formula

Ingredients & Dosages

Serving size: Take 2 capsules daily (1 during the day and 1 in the evening). Do not exceed 2 capsules per day.

Ingredient Amount Per Serving Purpose
Proprietary Blend of Probiotic Bacteria (MAKTREK® Bi-Pass Technology; Lactobacillus acidophilus La-14; Bifidobacterium lactis Bl-04; Lactobacillus plantarum Lp-115; Lactobacillus paracasei Lpc-37) 800 mg (40 Billion CFU) Probiotic blend
Complex Marine Polysaccharide 60 mg Listed on the label
Fructooligosaccharide (FOS) 24 mg Prebiotic fiber

† Daily Value not established. Other ingredients: Hypromellose (vegetable capsule), Rice Maltodextrin, L-Leucine.

Science

Clinical Evidence

Published research relevant to this product. These studies were generally not conducted on this specific product.

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A systematic review and meta-analysis of 53 randomized trials of probiotics in 5,545 adults with irritable bowel syndrome found that particular combinations or strains appeared to have beneficial effects on global symptoms and abdominal pain, but definitive conclusions about which probiotics are effective could not be drawn. Adverse events were no more common with probiotics.
Ford AC et al. Aliment Pharmacol Ther, 2018;48(10):1044-1060. ↗
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A systematic review and meta-analysis of 63 randomized trials (11,811 participants) found probiotic administration was associated with a lower risk of antibiotic-associated diarrhea (relative risk 0.58, 95% CI 0.50 to 0.68). The authors noted significant heterogeneity and that the evidence was insufficient to determine which probiotics work best or for whom.
Hempel S et al. JAMA, 2012;307(18):1959-69. ↗
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A Cochrane review of 47 trials (15,260 participants) concluded that probiotics may reduce Clostridioides difficile-associated diarrhea (risk ratio 0.50) and antibiotic-associated diarrhea (risk ratio 0.67) in people taking antibiotics, both rated low-certainty evidence. Authors' affiliation with or funding from probiotic companies was noted in 28 of the studies.
Esmaeilinezhad Z et al. Cochrane Database Syst Rev, 2025;9(9):CD006095. ↗
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In a study in mice and human volunteers, probiotics given after antibiotics were associated with delayed and persistently incomplete recovery of the gut microbiome compared with spontaneous recovery, while autologous fecal microbiome transplantation led to rapid recovery. The authors suggested potential post-antibiotic probiotic benefits may be offset.
Suez J et al. Cell, 2018;174(6):1406-1423.e16. ↗
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A review of probiotic mixtures found beneficial effects on several end points, but only 16 studies compared a mixture with its component strains separately; in 12 of them (75%) the mixture was more effective. The authors state it is unclear whether this is due to synergy between strains or the higher dose used in some studies.
Chapman CM et al. Eur J Nutr, 2011;50(1):1-17. ↗
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A laboratory simulation of upper gastrointestinal passage and colonic fermentation tested a mixture of the four strains named on this label (B. lactis Bl-04, L. acidophilus La-14, L. paracasei Lpc-37, L. plantarum Lp-115) at 7 x 10^9 and 7 x 10^10 CFU and found a dose-response in recovery of all four strains. This was not a study in people, and its authors were employees of the strains' manufacturer.
Forssten S et al. Microorganisms, 2020;8(1):112. ↗
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A review of rapidly fermentable prebiotic substrates (inulin, fructo-oligosaccharides, galacto-oligosaccharides) concluded that they may support beneficial microbial and metabolic responses in tolerant individuals but may contribute to gas production, luminal distension and symptoms in susceptible individuals.
Ibrahim F. Clin Nutr ESPEN, 2026;76:105130. ↗
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A meta-analysis of 105 randomized trials (6,826 participants) concluded that probiotics gave minor but consistent improvements in several metabolic risk factors in people with metabolic diseases; improvements in body weight were seen in overweight but not obese participants. Several authors were employed by or received funding from Danone Research.
Koutnikova H et al. BMJ Open, 2019;9(3):e017995. ↗
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A review of probiotic safety concluded that probiotics have an excellent overall safety record but should be used with caution in certain patient groups, particularly neonates born prematurely and people with immune deficiency, and that the effects of one strain should not be generalized to others.
Boyle RJ et al. Am J Clin Nutr, 2006;83(6):1256-64. ↗
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A review reported that Lactobacillus bloodstream infection is infrequent but has risk factors including severe underlying disease, immune suppression, intensive care admission and central venous catheters; Lactiplantibacillus plantarum and Lacticaseibacillus paracasei were among the probiotics linked by molecular methods to blood isolates from some patients.
Kullar R et al. Microorganisms, 2023;11(4):896. ↗
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In a randomized trial of 298 patients with predicted severe acute pancreatitis, a multispecies probiotic given enterally did not reduce infectious complications and was associated with higher mortality (16% vs 6%); the authors concluded it should not be given to this category of patients.
Besselink MG et al. Lancet, 2008;371(9613):651-659. ↗
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A narrative expert review reported that nausea, vomiting, diarrhea and constipation are established effects of GLP-1 receptor agonist medicines, occurring in approximately 30% to 50% of patients, mostly during initiation and dose escalation.
Singhani V et al. Nutr Clin Pract, 2026;41(5):1318-1333. ↗
🔬 All studies referenced are peer-reviewed and published in indexed medical journals. This information is for educational purposes and does not constitute medical advice.
  • Four probiotic strains, 40 billion CFU per 2-capsule serving
  • Includes fructooligosaccharide (a prebiotic fiber) and a marine polysaccharide complex

Probiotic 40 Billion with Prebiotics combines four probiotic strains (Lactobacillus acidophilus La-14, Bifidobacterium lactis Bl-04, Lactobacillus plantarum Lp-115 and Lactobacillus paracasei Lpc-37) with fructooligosaccharide, a prebiotic fiber, and a complex marine polysaccharide. According to the Supplement Facts panel, one serving (2 capsules) provides 40 billion CFU. Probiotic effects are strain-specific, and the studies described below were not done on this product.

Evidence Rating★★★★★Limited evidence · Results of probiotic trials vary by strain and are often rated low certainty; no trials of this exact product were found

✓ Third-party tested  ·  GMP-certified manufacturing facility (NSF International)  ·  See testing standards ›

Ingredients: Proprietary Blend of Probiotic Bacteria: MAKTREK® (Bi-Pass Technology), Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04), Lactobacillus plantarum (Lp-115), Lactobacillus paracasei (Lpc-37); Complex Marine Polysaccharide; Fructooligosaccharide. Other ingredients: Hypromellose (vegetable capsule), rice maltodextrin, L-leucine.

Science behind this product

MAKTREK® Bi-Pass Technology: This is the manufacturer's name for the delivery system in the blend. No published studies of it were found in PubMed, so no claim about survival through digestion or shelf life is made here.

Probiotics and Antibiotic-Associated Diarrhea: A meta-analysis of 63 trials (11,811 participants) found probiotic use was associated with a lower risk of antibiotic-associated diarrhea (relative risk 0.58), but the results varied widely between trials and the authors could not say which probiotics work best. A 2025 Cochrane review rated the certainty of this evidence as low. Hempel 2012 · Cochrane 2025

Probiotic Safety: A safety review described an excellent overall safety record for probiotics, with caution advised for premature infants and people with immune deficiency. Rare bloodstream infections linked to probiotic bacteria have been reported in susceptible people. Boyle 2006 · Doron 2015 · Kullar 2023

Probiotics and Metabolic Measures: A meta-analysis of 105 randomized trials reported minor but consistent improvements in several metabolic measures in people with metabolic disease (for example body weight in overweight, not obese, participants). Findings depended on the strains used, and several authors were employed by or received funding from Danone Research. This is not a claim about this product. Koutnikova 2019

Manufacturer Country: USA | Amount: 60 caps | Suggested Use: Take 1 capsule during the day and 1 in the evening. Do not exceed 2 capsules per day.

Warning: Keep out of reach of children. Do not use if safety seal is damaged. Store in a cool, dry place. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease.

Gluten-free Lactose-free Allergen-free Sugar-free

Frequently Asked Questions

What is the CFU count in Kasivit Probiotic?
The Supplement Facts panel lists a proprietary blend of 800 mg providing 40 billion CFU per serving (2 capsules). The blend contains MAKTREK® (Bi-Pass Technology), Lactobacillus acidophilus La-14, Bifidobacterium lactis Bl-04, Lactobacillus plantarum Lp-115 and Lactobacillus paracasei Lpc-37. The label does not state a CFU count at the end of shelf life.

When is the best time to take this probiotic?
The suggested use is 1 capsule during the day and 1 in the evening, with a maximum of 2 capsules per day. No study was found that compares times of day for this product.

Is it safe to take with GLP-1 medications like Ozempic?
No studies of this product with GLP-1 medicines were found. Nausea, vomiting, diarrhea and constipation are common effects of GLP-1 medicines, and prebiotic fibers such as fructooligosaccharide can cause gas or bloating in some people. Ask your prescriber or pharmacist before adding this supplement.

Who should talk to a clinician before taking this probiotic?
Ask a doctor or pharmacist first if you are pregnant or breastfeeding, have a weakened immune system, a central venous catheter, a serious illness or a pancreas condition, or take prescription medicines. Do not give it to premature infants. Ask a clinician before giving it to children.

Questions

Frequently Asked Questions