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Kasivit

Kasivit NAD+ Capsules

Name: Kasivit NAD+ Capsules
Brand: Kasivit
SKU: JTP4NADP
Price: 60.0 USD
Availability: InStock

Kasivit NAD+ capsules: per 2-capsule serving, NAD+ 500 mg, quercetin dihydrate extract 250 mg and Japanese knotweed extract (98% resveratrol) 150 mg; 30 servings (60 capsules). Human trials of NAD+ precursors raised blood NAD levels but have not shown clear health benefits. Ask a doctor first if you take medicines.

💊2 capsules (one serving; 30 servings per container). Supplier suggested use: adults take two (2) capsules daily with 6 oz (177 ml) of water, or as directed by a healthcare professional. Do not exceed the recommended dose.

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Key Benefits

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Three Ingredients, Amounts From the Label

Per serving of 2 capsules (30 servings per container) the label lists NAD+ 500 mg, quercetin dihydrate extract (Sophora japonica flower bud) 250 mg and Japanese knotweed extract (98% resveratrol; Polygonum cuspidatum root) 150 mg, which is about 147 mg of resveratrol if the 98% applies to the whole 150 mg. It lists no NMN and no NR. The ingredients have been studied mostly on their own, in other forms and amounts; this product has not been studied.

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NAD+ Precursors: Blood Levels Rise, Clinical Benefit Not Shown

A 2026 systematic review of 33 human studies found that oral NR and NMN consistently raised blood or cell NAD markers, but effects on function and other healthspan outcomes were heterogeneous and often null, and it called clinical effectiveness for anti-aging or wellness outcomes inconclusive. In an 8-week company-funded trial, NR at 100, 300 and 1,000 mg a day raised whole-blood NAD+ by 22%, 51% and 142%; NMN trials used 250 to 2,000 mg a day. NAD+ is a larger molecule than NR or NMN, so those milligram amounts do not translate to the 500 mg of NAD+ here. The only oral NAD+ trial found tested a specially processed formulation for 5 days (53% higher whole-blood NAD than placebo, dose not given in the abstract) and reported no confirmed clinical benefit.

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Blood NAD+ Did Not Vary With Age in a 2026 Analysis

NAD+ is often described as falling with age, but an analysis of seven human cohorts found whole-blood NAD+ stable with age and across lifestyle interventions. Whether supplements correct an age-related deficit is therefore not established, and no trial has shown that NAD+ supplements slow aging in people.

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Quercetin and Resveratrol: Small or Mixed Results, at Different Amounts

A meta-analysis of 7 trials (587 people) found quercetin lowered blood pressure slightly (about 3 mmHg systolic); the change was significant in trials at 500 mg a day or more and not in those below 500 mg, although the difference between dose groups was not significant. This product provides 250 mg of quercetin dihydrate extract per serving. An umbrella review found a smaller effect (about 1.9 mmHg). For resveratrol, one trial gave 75 mg twice daily (150 mg a day, as in one serving here) to postmenopausal women for 12 months and reported higher bone density than placebo; a systematic review in older adults found benefits in some groups, no advantage over placebo in people with diabetes or peripheral artery disease, and higher doses raised some cardiovascular risk markers.

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Check With a Clinician First

Long-term safety of NAD+ supplements is not known, and safety in pregnancy, breastfeeding and children has not been established. Quercetin 500 mg three times a day raised blood levels of the medicine fexofenadine by 55% in healthy volunteers (this product has 250 mg per serving; interactions at that amount were not studied), and laboratory work suggests resveratrol can inhibit a liver enzyme (CYP3A4) that handles many medicines. A 2025 review lists resveratrol among antioxidants that can interfere with blood clotting, and resveratrol can act as a phytoestrogen. Speak with a doctor or pharmacist before use if you take medicines, especially blood thinners, or have or have had cancer or a hormone-sensitive condition.

✅This product is for you if…

Adults who want a supplement listing NAD+ 500 mg, quercetin 250 mg and resveratrol 150 mg per serving and who understand that human trials of NAD+ precursors have not shown clear health benefits
Adults who have first asked a doctor or pharmacist whether it suits them, especially if they take medicines or have a medical condition

⚠️Consult your healthcare provider if…

You are pregnant, breastfeeding or trying to conceive: ask your doctor first (safety has not been established; the EFSA assessment of NMN excluded pregnant and lactating women)
The person is a child or under 18: do not give it to a child unless a doctor advises it
You have or have had cancer, or are having cancer treatment: speak with your oncologist first (NAD+ precursors reduced the effect of chemotherapy in cell and mouse studies)
You take prescribed medicines, including blood thinners: ask your prescriber or pharmacist first (quercetin raised fexofenadine levels by 55% in volunteers at 1,500 mg a day; resveratrol inhibited a drug-metabolising enzyme in laboratory tests and is listed in a 2025 review among antioxidants that can interfere with blood clotting)
You take blood-pressure medicines: ask your prescriber or pharmacist first (quercetin lowered blood pressure slightly in trials, mainly at 500 mg a day or more)
You have kidney disease, liver disease or a hormone-sensitive cancer or condition: speak with your doctor first (resveratrol can act as a phytoestrogen; animal studies suggest possible risks of high-dose quercetin for damaged kidneys and estrogen-dependent tumours)
You are due to have surgery: tell your surgeon or doctor that you take it, because resveratrol is listed among antioxidants that can interfere with blood clotting
You are allergic to any ingredient on the label (NAD+, quercetin dihydrate extract from Sophora japonica, Japanese knotweed extract, brown rice flour, olive oil)
Never stop or change a prescribed medicine without asking your prescriber

Formula

Ingredients & Dosages

Serving size: 2 capsules (one serving; 30 servings per container). Supplier suggested use: adults take two (2) capsules daily with 6 oz (177 ml) of water, or as directed by a healthcare professional. Do not exceed the recommended dose.

Ingredient	Amount Per Serving	Purpose
NAD+ (nicotinamide adenine dinucleotide)	500 mg per serving (2 capsules); no % Daily Value stated	Coenzyme
Quercetin dihydrate extract (Sophora japonica, whole flower bud)	250 mg per serving (2 capsules); no % Daily Value stated	Flavonoid (plant extract)
Japanese knotweed extract (98% resveratrol; Polygonum cuspidatum root)	150 mg per serving (2 capsules); no % Daily Value stated	Polyphenol (plant extract)

† Daily Value not established. Other ingredients: HPMC (vegetable capsule), Microcrystalline Cellulose (MCC), Brown Rice Flour, Olive Oil, Silicon Dioxide, Magnesium Stearate.

Science

Clinical Evidence

Published research relevant to this product. These studies were generally not conducted on this specific product.

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A systematic review of 33 human intervention studies of NAD+-boosting compounds found that oral NR and NMN consistently raised blood or cellular NAD-related markers and were generally well tolerated over weeks to months, but effects on functional, metabolic, vascular and other healthspan outcomes were heterogeneous and often null; no eligible outcomes trials of intravenous or intramuscular NAD+ for anti-aging or wellness were found, and the authors concluded that clinical effectiveness for anti-aging or wellness outcomes remains inconclusive

Gallagher C, Emmanuel OO. Ageing Res Rev. 2026;116:103057. ↗

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Across seven independent human cohorts, whole-blood NAD+ levels remained stable with age and across lifestyle interventions but changed in response to nicotinamide riboside supplementation; the authors questioned the usefulness of blood NAD+ as a marker of ageing

Trętowicz MM et al. Nat Metab. 2026;8(6):1282-1290. ↗

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In a 5-day placebo-controlled trial in healthy adults aged 45 to 75 (60 randomised, 50 analysed), a specially processed oral NAD+ formulation (LNAD+) raised whole-blood intracellular NAD by 53% versus placebo without changing plasma NAD; no secondary clinical, vital-sign or wellbeing endpoint remained significant after correction for multiple testing (one mild adverse event of nausea in the LNAD+ group). This is the only human trial of oral NAD+ itself found, and it tested a specific formulation

Kornilov SA et al. Geroscience. 2026 Jul 30. ↗

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In a 12-week placebo-controlled pilot trial in 42 adults with amnestic mild cognitive impairment, nicotinamide riboside doubled blood NAD+ but did not improve cognitive function, total cerebral blood flow or blood pressure

Martens CR et al. Alzheimers Dement. 2026;22(7):e71605. ↗

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The European Food Safety Authority's 2026 opinion judged NMN (not NAD+) safe as a food-supplement ingredient at up to 300 mg/day for adults, excluding pregnant and lactating women; a 90-day rat study showed effects on reproductive organs

EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) et al. EFSA J. 2026;24(5):e10007. ↗

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In pancreatic cancer cells and in mice, the NAD+ precursors NMN and nicotinamide increased resistance to chemotherapy and supported cancer growth; the authors called for careful evaluation of NAD+-boosting supplements in people with active cancer

Nakazzi F et al. Cancer Lett. 2026;645:218334. ↗

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A meta-analysis of 7 randomised trials (587 people) found that quercetin supplementation lowered systolic blood pressure by about 3 mmHg and diastolic by about 2.6 mmHg; the effect was significant in trials at 500 mg/day or more and not significant below 500 mg/day, although the test for a difference between the dose groups was not significant; the authors said further studies are needed on clinical relevance

Serban MC et al. J Am Heart Assoc. 2016;5(7):e002713. ↗

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An umbrella review of meta-analyses of quercetin trials found a reduction in systolic blood pressure (about 1.9 mmHg) and insulin level but no effect on diastolic blood pressure, lipids, inflammation or fasting glucose; certainty of evidence ranged from very low to moderate

Arabi SM et al. Phytother Res. 2023;37(11):5080-5091. ↗

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A review of quercetin as a dietary supplement found adverse effects were rarely reported and mild, but data on long-term use (over 12 weeks) of high doses (1,000 mg or more) are not available; animal studies suggested possible risks for damaged kidneys and estrogen-dependent cancer, and some drug interactions were identified

Andres S et al. Mol Nutr Food Res. 2018;62(1). ↗

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In 12 healthy volunteers, quercetin 500 mg three times daily for 7 days raised the blood exposure (AUC) of the medicine fexofenadine by 55%, probably by inhibiting P-glycoprotein

Kim KA et al. Eur J Clin Pharmacol. 2009;65(6):609-614. ↗

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A systematic review of 10 randomised trials of resveratrol in older adults reported benefits in some groups (with exercise, and potential neuroprotective effects in Alzheimer's disease), no advantage over placebo in people with diabetes or peripheral artery disease, and higher doses increased some cardiovascular risk biomarkers in overweight people; no significant adverse events were reported, but optimal dose, long-term effects and medicine interactions still need study

Yadegar S et al. Phytother Res. 2024;38(5):2448-2461. ↗

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In 40 healthy volunteers taking resveratrol 0.5 to 5 g daily for 29 days, the 2.5 g and 5 g doses caused mild to moderate gastrointestinal symptoms

Brown VA et al. Cancer Res. 2010;70(22):9003-9011. ↗

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In laboratory experiments with human liver cells and microsomes, trans-resveratrol inhibited the enzyme CYP3A4/5 at micromolar concentrations, which the authors said suggests a potential risk of food-drug interactions; this was not a study in people

Hyrsova L et al. Toxicol Lett. 2019;300:81-91. ↗

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In an 8-week placebo-controlled trial in healthy overweight adults, nicotinamide riboside 100, 300 and 1,000 mg a day raised whole-blood NAD+ by 22%, 51% and 142% within 2 weeks, with no significant difference in adverse events versus placebo; the trial was funded by the NR supplier and two authors are its employees

Conze D et al. Sci Rep. 2019;9(1):9772. ↗

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A systematic review and meta-analysis of 15 randomised trials of oral NMN (doses 250 to 2,000 mg/day, 14 days to 24 weeks; 10 trials in the safety analyses) found no increase in adverse events or in liver enzymes and no significant effects on body weight, fasting glucose, HbA1c, lipids or systolic blood pressure; diastolic blood pressure fell slightly, and the authors called for larger, longer trials

Yang W et al. Nutrients. 2026;18(14):2251. ↗

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In the RESHAW trial, a 24-month randomised crossover trial in postmenopausal women, resveratrol 75 mg twice daily (150 mg a day) for 12 months was associated with higher bone density in the lumbar spine and femoral neck and a 7.24% lower bone-resorption marker than placebo; the abstract describes resveratrol as able to act as a phytoestrogen

Wong RH et al. J Bone Miner Res. 2020;35(11):2121-2131. ↗

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A 2025 review of supplements used for cardiovascular protection listed resveratrol among antioxidant agents that can interfere with hemostasis, metabolism or redox-sensitive pathways, and noted that several other supplements increase bleeding risk when combined with antithrombotic therapy; the abstract gives no resveratrol-specific data

Dobre MZ et al. Int J Mol Sci. 2025;26(20):10183. ↗

🔬 All studies referenced are peer-reviewed and published in indexed medical journals. This information is for educational purposes and does not constitute medical advice.

Per 2-capsule serving: NAD+ 500 mg, quercetin dihydrate extract 250 mg and Japanese knotweed extract (98% resveratrol) 150 mg; the label lists no NMN or NR
In human trials, NAD+ precursors raised blood NAD levels, but clear health benefits have not been shown
Ask a doctor or pharmacist first if you take medicines, are pregnant or breastfeeding, or have or have had cancer
Capsule: HPMC (vegetable capsule)

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells, where it takes part in energy metabolism and DNA repair. The Supplement Facts label lists, per serving of 2 capsules (30 servings per container), NAD+ 500 mg, quercetin dihydrate extract 250 mg and Japanese knotweed extract (98% resveratrol) 150 mg. It lists no NMN (nicotinamide mononucleotide) and no NR (nicotinamide riboside).*

Most human trials of this kind of supplement have tested the NAD+ precursors NR and NMN rather than NAD+ itself. In those trials blood NAD levels rose, but a 2026 systematic review concluded that clinical effectiveness for anti-aging or wellness outcomes remains inconclusive, and a 2026 analysis of seven human cohorts found that whole-blood NAD+ did not vary with age. In meta-analyses, quercetin was linked to a small fall in blood pressure, mainly in trials giving 500 mg a day or more (this product provides 250 mg per serving), and trial results for resveratrol are mixed (one 12-month trial in postmenopausal women used 150 mg a day, the amount in one serving here). The only oral NAD+ trial found tested a specially processed formulation for 5 days. No study of this product, or of the three ingredients together, is cited on this page. Quercetin and resveratrol can interact with some medicines, and long-term safety is not known.*

Evidence Rating★★★★★Very limited evidence · Human trials of NAD+ precursors raised blood NAD levels but have not shown clear health benefits; results for quercetin and resveratrol are small or mixed; no study of this product is cited

✓ Third-party tested · GMP-certified manufacturing facility (UL Solutions) · See testing standards ›

Ingredients: NAD+ (Nicotinamide Adenine Dinucleotide) (500 mg), Quercetin Dihydrate Extract (250 mg), Japanese Knotweed Extract (98% Resveratrol) (150 mg), HPMC (vegetable capsule), Microcrystalline Cellulose (MCC), Brown Rice Flour, Olive Oil, Silicon Dioxide, Magnesium Stearate.

Manufacturer's country: USA | Product amount: 60 capsules / 1.8 oz / 50 g | Gross weight: 2.4 oz / 68 g

Suggested use: As a dietary supplement, adults take two (2) capsules daily. For best results, take with 6oz (177ml) of water or as directed by healthcare professional.

Warning: Do not exceed recommended dose. KEEP OUT OF THE REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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