Kasivit

Kasivit Magnesium Glycinate Capsules

Kasivit Magnesium Glycinate: 275 mg elemental magnesium per 3-capsule serving, from 2,500 mg magnesium glycinate. 90 capsules, 30 servings.

💊Take three (3) capsules once daily, preferably at bedtime, or as directed by your healthcare professional (275 mg elemental magnesium from 2,500 mg magnesium glycinate per serving).
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🧪 Third-Party Tested
🇺🇸 Manufactured in the USA using globally sourced ingredients
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🔬 Evidence-Rated

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Bronze Evidence Rating

Emerging research tier · Limited human research exists on the main ingredient. This describes published research, not this product.

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This rating describes how much published human research we found on the main ingredient. It is not a test or review of this product, it does not mean the product treats or prevents any condition, and it is not medical advice. View the Evidence Standard →

Why It Works

Key Benefits

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275 mg Elemental Magnesium per Serving
Each 3-capsule serving provides 275 mg of elemental magnesium from 2,500 mg of magnesium glycinate (magnesium bound to the amino acid glycine). The US upper limit for magnesium from supplements is 350 mg per day for adults; it was set in 1997 with diarrhea as the limiting factor and does not apply to magnesium from food. Count the magnesium from all supplements you take.
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Sleep: Small or Mixed Results in Studies
In a 4-week trial of 155 adults reporting poor sleep, 250 mg of elemental magnesium daily as bisglycinate lowered Insomnia Severity Index scores slightly more than placebo (-3.9 vs -2.3 points), and the authors called the effect size small. Reviews describe the overall evidence for magnesium and sleep as limited or uncertain. This product was not studied.
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Stress: Linked to Magnesium Status, Not a Proven Effect
Reviews report low magnesium status in several studies of people with psychological stress and propose that stress and low magnesium may reinforce each other. They do not show that taking a magnesium supplement reduces stress. In the bisglycinate sleep trial, other psychological outcomes did not differ from placebo.
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Blood Pressure: Small Average Change in a Meta-analysis
A meta-analysis of 34 placebo-controlled trials (2,028 participants) found that magnesium supplementation lowered systolic blood pressure by 2.00 mm Hg and diastolic by 1.78 mm Hg compared with placebo, at a median dose of 368 mg per day for about 3 months. This is a small average change and not a claim about this product. Ask your doctor first if you take blood-pressure medicines.
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Bone: Evidence Is Mostly Observational
A narrative review reported that lower serum magnesium was related to osteoporosis and that lower magnesium intake was associated with lower bone mineral density and higher fracture risk. Most supplementation studies it covered used citrate, carbonate or oxide, not glycinate. It does not show that this product affects bone.
✅This product is for you if…
You want a magnesium glycinate supplement with 275 mg of elemental magnesium per 3-capsule serving
You prefer a once-daily supplement taken at bedtime, as in the suggested use
You have checked with your doctor or pharmacist if you have kidney disease or take regular medicines
⚠️Consult your healthcare provider if…
You have kidney disease or reduced kidney function: magnesium from supplements and laxatives can build up. Ask your doctor first
You are pregnant or breastfeeding: ask your doctor first
Children: not intended for children. Ask a clinician before giving it to a child
You take antibiotics (for example fluoroquinolones or tetracyclines): magnesium can reduce absorption of some of them. Ask your pharmacist or prescriber how to space them
You take levothyroxine or other thyroid medicine: magnesium can reduce its absorption. Ask your pharmacist or prescriber how to space them
You take bisphosphonates for osteoporosis: ask your pharmacist or prescriber about spacing
You take diuretics or a proton pump inhibitor (these can lower magnesium levels): ask your prescriber or pharmacist first
You take blood-pressure medicines: ask your prescriber or pharmacist first
You already take other magnesium supplements, magnesium-containing antacids or laxatives: the US upper limit for magnesium from supplements is 350 mg per day for adults. Ask a pharmacist before adding this product
You have persistent loose stools or another bowel condition: ask a clinician first
Never stop or change a prescribed medicine without asking your prescriber
Formula

Ingredients & Dosages

Serving size: Take three (3) capsules once daily, preferably at bedtime, or as directed by your healthcare professional (275 mg elemental magnesium from 2,500 mg magnesium glycinate per serving).

Ingredient Amount Per Serving Purpose
Magnesium (as Magnesium Glycinate) 275 mg All magnesium functions — sleep, stress, muscle relaxation, cardiovascular, bone. Glycinate form chosen for superior absorption and GI tolerability vs oxide or citrate.

† Daily Value not established. Other ingredients: Hypromellose (capsule), Magnesium Stearate, Silicon Dioxide, Rice Flour.

Science

Clinical Evidence

Published research relevant to this product. These studies were generally not conducted on this specific product.

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In a 4-week randomized, double-blind, placebo-controlled trial of 155 adults aged 18-65 reporting poor sleep, 250 mg of elemental magnesium daily as bisglycinate reduced Insomnia Severity Index scores more than placebo (-3.9 vs -2.3 points; p = 0.049). The effect size was small (Cohen's d = 0.2) and other psychological outcomes did not differ from placebo. Exploratory analyses suggested larger improvements in people with lower dietary magnesium intake.
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In 46 older adults, 500 mg of magnesium daily for 8 weeks was associated with a lower Insomnia Severity Index score, shorter sleep onset latency and higher sleep time and sleep efficiency than placebo (total sleep time did not differ significantly between groups). The study was small and used a higher dose than one serving of this product.
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A systematic review of three randomized trials in 151 older adults with insomnia rated the evidence for oral magnesium as low to very low quality and concluded that the quality of the literature is not sufficient for well-informed recommendations. A 2024 correction to this paper has been published.
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A systematic review of 9 studies (7,582 people) found that observational studies suggested an association between magnesium status and sleep quality, while randomized trials showed an uncertain association between magnesium supplementation and sleep disorders.
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A Cochrane review of 11 trials (735 people) found that, for idiopathic muscle cramps in largely older adults, differences in cramp frequency between magnesium and placebo were small and not statistically significant (moderate-certainty evidence). Trials in pregnancy-associated leg cramps were rated at high risk of bias.
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A meta-analysis of 34 randomized, double-blind, placebo-controlled trials (2,028 participants) found that magnesium supplementation at a median dose of 368 mg per day for a median of 3 months reduced systolic blood pressure by 2.00 mm Hg (95% CI 0.43-3.58) and diastolic blood pressure by 1.78 mm Hg (95% CI 0.73-2.82) compared with placebo.
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Almost half (48%) of the US population consumed less than the required amount of magnesium from food in 2005-2006, down from 56% in 2001-2002. The authors reported that low magnesium intakes and blood levels have been associated with several chronic conditions; this is an association, not proof that supplements prevent them.
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A review reported low magnesium status in several studies of people with psychological stress and proposed that stress could increase magnesium loss and that magnesium deficiency could increase susceptibility to stress. It is a narrative review that does not test whether supplements reduce stress. Several authors are employed by Sanofi's consumer healthcare unit.
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A narrative review of 28 studies reported that lower serum magnesium was related to osteoporosis and that people with lower magnesium intake had lower bone mineral density and a higher fracture risk. The supplementation studies it covered mostly used citrate, carbonate or oxide (250-1800 mg), not glycinate.
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The US tolerable upper intake level for magnesium from supplements (350 mg per day for adults) was set in 1997 with diarrhea as the limiting factor. This perspective, written by authors from the Center for Magnesium Education and Research, argued that the limit should be re-evaluated; it found 7 of 10 identified studies (intakes of 128-1200 mg per day) reported no significant difference in diarrhea between magnesium and control groups. It does not change the 350 mg per day limit.
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In a retrospective study of 193 patients taking daily magnesium oxide (a laxative) for functional constipation, 10 (5.2%) had hypermagnesemia; chronic kidney disease (grade 4) and the magnesium oxide dose were associated with hypermagnesemia. The study did not involve magnesium glycinate.
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A case series described four elderly patients with constipation and kidney dysfunction who developed symptomatic hypermagnesemia from magnesium oxide, one with a fatal course; the authors noted that people with chronic kidney disease and the elderly are at risk when given magnesium. The cases involved magnesium oxide laxatives, not magnesium glycinate.
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A review of fluoroquinolone antibiotic interactions reported that absorption of all fluoroquinolones is almost entirely inhibited when taken with di- and trivalent cations such as the aluminum and magnesium in antacids, and that this can be significant even when doses are separated by hours.
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In a crossover study of 15 healthy adults, taking levothyroxine with magnesium aspartate reduced thyroxine absorption by 12% and with magnesium citrate by 7% (not statistically significant). The authors advised that people with hypothyroidism take levothyroxine separately from magnesium-containing products.
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A review noted that medication use, notably proton pump inhibitors, diuretics and chemotherapy agents, contributes to low magnesium status, and that serum magnesium is an insensitive marker of total body magnesium.
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In a 60-day randomized, double-blind, placebo-controlled study of 46 healthy adults taking 300 mg of elemental magnesium daily, an amino-acid chelate and magnesium citrate produced greater absorption than magnesium oxide, measured by 24-hour urinary magnesium excretion (P = 0.033). Magnesium citrate produced the highest serum magnesium. The study did not test magnesium glycinate by name.
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In a double-blind crossover trial of 12 patients who had undergone ileal resection, absorption of labeled magnesium was similar for magnesium diglycinate and magnesium oxide overall (23.5% vs 22.8%), but higher with diglycinate in the four patients who absorbed oxide worst (23.5% vs 11.8%). Results in people with this surgery may not apply to healthy adults.
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In a 2024 double-blind crossover study of 40 healthy adults, plasma magnesium rose significantly after a microencapsulated magnesium product, after magnesium oxide (at 1 hour) and after magnesium citrate (at 4 hours), but not significantly after magnesium bisglycinate. The study was funded by Lubrizol Life Science, whose employees were co-authors, and tested a microencapsulated ingredient.
🔬 All studies referenced are peer-reviewed and published in indexed medical journals. This information is for educational purposes and does not constitute medical advice.

Key Features:

  • 275 mg Elemental Magnesium Per Serving (3 capsules), from 2,500 mg Magnesium Glycinate
  • Supplemental magnesium can cause loose stools; ask a doctor first if you have kidney disease or take regular medicines
  • 30 Servings | 90 Capsules

Magnesium is a mineral that acts as a cofactor in hundreds of enzymatic reactions in the body. In one analysis, 48% of the US population consumed less than the required amount of magnesium from food in 2005-2006. Low intake is not the same as a deficiency, and not everyone needs a supplement. Studies of magnesium supplements have shown small or mixed effects on sleep, and no study of Kasivit Magnesium Glycinate itself is cited on this page.

Kasivit Magnesium Glycinate provides 275 mg of elemental magnesium per serving (three capsules), from 2,500 mg of magnesium glycinate (magnesium bound to the amino acid glycine). Studies comparing magnesium forms are few and their results are mixed, so this page does not claim that magnesium glycinate is absorbed better than other forms.

✓ Curated by the Kasivit Editorial Team

The Science Behind Magnesium Supplements

Magnesium and Sleep

In a 4-week randomized, placebo-controlled trial of 155 adults reporting poor sleep, 250 mg of elemental magnesium daily as bisglycinate lowered Insomnia Severity Index scores slightly more than placebo (-3.9 vs -2.3 points; p = 0.049); the authors called the effect size small. Reviews describe the overall evidence as limited: a review of three trials in older adults rated it low to very low quality, and a systematic review found uncertain results from randomized trials. Schuster 2025 · Mah 2021 · Arab 2023

Magnesium and Stress

A review reported low magnesium status in several studies of people with psychological stress and proposed that stress and low magnesium may reinforce each other. The review does not show that taking a magnesium supplement reduces stress. Pickering 2020

Magnesium and Bone

A narrative review of 28 studies reported that lower serum magnesium was related to osteoporosis and that people with lower magnesium intake had lower bone mineral density and a higher fracture risk. Most supplementation studies it covered used citrate, carbonate or oxide, not glycinate. Rondanelli 2021

Magnesium and Blood Pressure

A meta-analysis of 34 placebo-controlled trials found that magnesium supplementation (median dose 368 mg per day for a median of 3 months) lowered systolic blood pressure by 2.00 mm Hg and diastolic by 1.78 mm Hg compared with placebo. This is a small average change and is not a claim about this product. Zhang 2016

Safety

The US upper limit for magnesium from supplements is 350 mg per day for adults; it was set in 1997 with diarrhea as the limiting factor. In studies of magnesium oxide laxatives, high blood magnesium was reported mainly in people with chronic kidney disease. Ask a doctor first if you have kidney disease, and ask a doctor or pharmacist if you take regular medicines. Costello 2023 · Mori 2019 · Yamaguchi 2019

Supplement Facts: Serving Size: 3 Capsules | Servings Per Container: 30 | Magnesium 275 mg (65% DV) — from 2,500 mg Magnesium Glycinate

Other Ingredients: Hypromellose (capsule), Magnesium Stearate, Silicon Dioxide, Rice Flour.

Evidence Rating★★★★★Limited evidence · Magnesium supplements had a small effect on insomnia severity in one trial and mixed results in reviews; no study of this product is cited

✓ Third-party tested  ·  GMP-certified manufacturing facility (NSF International)  ·  See testing standards ›

Manufacturer Country: USA | Amount: 90 capsules (30 servings) | Gross Weight: 0.25 lb (113 g)

Suggested Use: Take three (3) capsules once daily, preferably at bedtime, or as directed by your healthcare professional.

Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Gluten-free Vegetarian Lactose-free Allergen-free Non-GMO Vegan friendly

Questions

Frequently Asked Questions