Coenzyme Q10 (CoQ10) is a compound found naturally in the body, where it takes part in the cell's energy-producing chain and acts as an antioxidant. Kasivit CoQ10 is a dietary supplement that contains CoQ10 in the ubiquinone form. Studies of CoQ10 supplements have given mixed results: for example, meta-analyses of randomised trials found no clear benefit for muscle pain in people taking statins, while a trial in people with heart failure reported fewer major cardiovascular events with CoQ10 added to standard care. This page describes those studies; no study of this product is cited.*
Evidence Rating★★★★★Limited and mixed evidence · Meta-analyses found no clear benefit of CoQ10 for statin muscle symptoms; a heart-failure trial is not specific to this product; no study of this product is cited
✓ Third-party tested · GMP-certified manufacturing facility (NSF International) · See testing standards ›
Ingredients: Coenzyme Q-10 (Ubiquinone), Cellulose (vegetable capsule), Rice Flour.
Science behind this product
CoQ10 and Antioxidant Markers
In a meta-analysis of 17 randomised trials (972 participants), CoQ10 raised blood levels of total antioxidant capacity and superoxide dismutase and lowered malondialdehyde compared with placebo. The authors advised that the results be taken with caution because research was limited. These are laboratory markers, not health outcomes. Source
CoQ10 and Statin Medicines
Statins lower blood CoQ10: across 8 placebo-controlled treatment arms, plasma CoQ10 fell by 0.44 µmol/L, and the authors noted that the clinical relevance is unclear. Source For statin muscle symptoms, a meta-analysis of 6 randomised trials (302 patients) found no significant benefit of CoQ10, Source and a 2020 meta-analysis of 7 trials (321 patients) did not find benefit for muscle pain or for staying on the statin. Source A small trial of 32 patients reported lower pain scores with CoQ10 100 mg/day, with no change in the vitamin E comparison group, Source whereas a trial of 600 mg/day ubiquinol in 41 people with confirmed statin muscle pain found no reduction in pain. Source
CoQ10 in Heart Failure and Blood Pressure Studies
In the Q-SYMBIO trial of 420 people with moderate to severe heart failure on standard therapy, CoQ10 300 mg/day was associated with fewer major cardiovascular events over 2 years (15% vs 26%), while 16-week endpoints did not change significantly. This result applies to people with heart failure, not to people who take CoQ10 for general health. Source A 2025 meta-analysis of 45 randomised trials found systolic blood pressure about 3.4 mmHg lower with CoQ10, with no significant effect on diastolic pressure or heart rate. Source
Manufacturer Country: USA | Product Amount: 30 caps | Gross Weight: 0.25lb (113g)
Suggested Use: Take one (1) capsule twice a day as a dietary supplement. For best results, take 20-30 min before a meal or as directed by your healthcare professional.
Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place. The Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.
