Kasivit

Kasivit CoQ10 Supplement 200mg — Ubiquinone | 30 Capsules

Kasivit CoQ10 Supplement: coenzyme Q10 (ubiquinone) in a vegetable capsule. Studies of CoQ10 are mixed; ask your prescriber or pharmacist first if you take a statin, warfarin or other medicines.

💊1 capsule (one serving; 30 servings per container). Supplier suggested use: 1 capsule twice a day as a dietary supplement, 20-30 minutes before a meal, or as directed by a healthcare professional. Follow the label and do not exceed the recommended amount.
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🧪 Third-Party Tested
🇺🇸 Manufactured in the USA using globally sourced ingredients
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🔬 Evidence-Rated

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Bronze Evidence Rating

Emerging research tier · Limited human research exists on the main ingredient. This describes published research, not this product.

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This rating describes how much published human research we found on the main ingredient. It is not a test or review of this product, it does not mean the product treats or prevents any condition, and it is not medical advice. View the Evidence Standard →

Why It Works

Key Benefits

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What CoQ10 Is
CoQ10 is found naturally in the body and acts as an electron carrier in the cell's energy-producing chain. A meta-analysis of 17 trials found that CoQ10 raised blood levels of antioxidant markers compared with placebo; the authors advised caution because research was limited, and these are laboratory markers, not health outcomes. This product contains CoQ10 as ubiquinone (supplier ingredient list).
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Statins Lower Blood CoQ10
In a meta-analysis of 8 placebo-controlled treatment arms, statins lowered plasma CoQ10 by about 0.44 µmol/L. A review found insufficient evidence from human studies that statins cause pathologically low CoQ10 in tissues, so what this means for muscle symptoms is not established.
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Statin Muscle Symptoms: Mixed Results
A meta-analysis of 6 trials (302 patients) and a 2020 meta-analysis of 7 trials (321 patients) did not show a benefit of CoQ10 for statin muscle pain. A small 32-patient trial reported lower pain scores with CoQ10 100 mg/day and no change in the vitamin E comparison group, while a trial of 600 mg/day ubiquinol in 41 people with confirmed statin muscle pain found no reduction. Talk to your prescriber; do not stop or change a statin without asking.
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Heart Failure and Blood Pressure Studies
In the Q-SYMBIO trial in 420 people with moderate to severe heart failure on standard therapy, CoQ10 300 mg/day was associated with fewer major cardiovascular events over 2 years (15% vs 26%). It does not show that CoQ10 prevents heart events in other people. A 2025 meta-analysis of 45 trials found systolic blood pressure about 3.4 mmHg lower, with no significant effect on diastolic pressure or heart rate.
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Check Medicines First
A case report described a weaker warfarin response in a woman taking CoQ10, which returned to the earlier level after CoQ10 was stopped, while a crossover trial of 24 people taking 100 mg/day found no change in warfarin dose. CoQ10 may also lower blood pressure slightly. Ask your prescriber or pharmacist before use if you take warfarin or other blood thinners, blood-pressure medicines, diabetes medicines or chemotherapy.
✅This product is for you if…
Adults who want a CoQ10 (ubiquinone) supplement and have checked the precautions in the list below
Adults who take a statin and want to discuss CoQ10 with their prescriber first (trials on statin muscle symptoms are mixed)
Adults who take other medicines or have a heart condition and have first asked a doctor or pharmacist whether CoQ10 suits them
⚠️Consult your healthcare provider if…
You are pregnant or breastfeeding: ask your doctor first (no data on use in pregnancy were reviewed)
The person is a child or under 18: do not give CoQ10 to a child unless a doctor advises it
You take warfarin or another blood thinner (a case report described a weaker warfarin response with CoQ10): ask your prescriber or pharmacist first
You take a statin: ask your prescriber before adding CoQ10; do not stop or change the statin on your own, and report severe muscle pain, marked weakness or dark urine promptly
You take blood-pressure medicines (a meta-analysis found CoQ10 lowered systolic blood pressure by about 3.4 mmHg): ask your prescriber or pharmacist first
You take diabetes medicines (a case report described insulin autoimmune syndrome possibly caused by CoQ10): ask your prescriber or pharmacist first
You are having chemotherapy (data are limited): ask your oncology team first
You have heart failure or another heart condition: speak with your doctor before use
You have liver or kidney disease or another medical condition: speak with your doctor before use
You have surgery planned: tell your surgeon about all supplements you take
You are allergic to any ingredient on the label (rice flour, cellulose)
Never stop or change a prescribed medicine without asking your prescriber
Formula

Ingredients & Dosages

Serving size: 1 capsule (one serving; 30 servings per container). Supplier suggested use: 1 capsule twice a day as a dietary supplement, 20-30 minutes before a meal, or as directed by a healthcare professional. Follow the label and do not exceed the recommended amount.

Ingredient Amount Per Serving Purpose
Coenzyme Q10 (Ubiquinone) 200 mg Mitochondrial energy production (ATP synthesis), cardiovascular support, antioxidant protection

† Daily Value not established. Other ingredients: Cellulose (vegetable capsule), Rice Flour.

Science

Clinical Evidence

Published research relevant to this product. These studies were generally not conducted on this specific product.

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In a meta-analysis of 8 placebo-controlled statin treatment arms, statins lowered plasma CoQ10 by 0.44 µmol/L (significant for atorvastatin, simvastatin, rosuvastatin and pravastatin); the authors noted that the clinical relevance is unclear and called for further trials
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A review found insufficient evidence from human studies to link statin therapy unequivocally to pathologically low tissue CoQ10; the authors noted that plasma CoQ10 has limited value as a measure of cell levels
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A systematic review concluded there is insufficient evidence that CoQ10 deficiency causes statin-associated myopathy, that data on CoQ10 supplementation and muscle symptoms are scarce and contradictory, and that routine CoQ10 use in statin-treated patients cannot be recommended
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In a meta-analysis of 6 randomised trials (302 patients taking statins), CoQ10 had no significant effect on muscle pain (a trend toward less pain did not reach significance) or on plasma creatine kinase; the authors concluded the results do not suggest a significant benefit
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A meta-analysis of 7 randomised trials (321 patients) did not show a benefit of CoQ10 for statin-associated muscle pain or for the proportion of patients staying on the statin
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In 32 statin users with muscle symptoms, pain severity fell by 40% after 30 days of CoQ10 100 mg/day, with no change in the vitamin E comparison group (small trial; vitamin E rather than an inactive placebo was the comparison)
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In 41 people with confirmed statin muscle pain, CoQ10 600 mg/day (ubiquinol) for 8 weeks did not reduce muscle pain compared with placebo
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In 420 people with moderate to severe heart failure on standard therapy, CoQ10 100 mg three times daily was associated with fewer major adverse cardiovascular events at 2 years (15% vs 26%); 16-week endpoints did not change significantly. The trial was in people with heart failure
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In a meta-analysis of 45 randomised trials, CoQ10 lowered systolic blood pressure by about 3.4 mmHg, with no significant effect on diastolic blood pressure or heart rate
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In a meta-analysis of 17 randomised trials (972 participants), CoQ10 raised serum total antioxidant capacity and superoxide dismutase and lowered malondialdehyde compared with placebo; the authors advised that results be taken with caution because research was limited
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A case report described a 72-year-old woman on warfarin with a weaker response after taking CoQ10, which returned to the earlier level when CoQ10 was stopped
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In a randomised crossover trial of 24 people on stable long-term warfarin, CoQ10 100 mg daily for 4 weeks did not change the warfarin dose or INR
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In a risk assessment, the authors judged that reports of nausea and other digestive effects of CoQ10 could not be linked to the dose, because they were no more common at 1,200 mg/day than at 60 mg/day
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In an early-phase study of women receiving doxorubicin chemotherapy for breast cancer, CoQ10 300 mg/day did not change doxorubicin pharmacokinetics; only 6 patients received that dose and the trial closed early because of slow accrual
🔬 All studies referenced are peer-reviewed and published in indexed medical journals. This information is for educational purposes and does not constitute medical advice.

Coenzyme Q10 (CoQ10) is a compound found naturally in the body, where it takes part in the cell's energy-producing chain and acts as an antioxidant. Kasivit CoQ10 is a dietary supplement that contains CoQ10 in the ubiquinone form. Studies of CoQ10 supplements have given mixed results: for example, meta-analyses of randomised trials found no clear benefit for muscle pain in people taking statins, while a trial in people with heart failure reported fewer major cardiovascular events with CoQ10 added to standard care. This page describes those studies; no study of this product is cited.*

Evidence Rating★★★★★Limited and mixed evidence · Meta-analyses found no clear benefit of CoQ10 for statin muscle symptoms; a heart-failure trial is not specific to this product; no study of this product is cited

✓ Third-party tested  ·  GMP-certified manufacturing facility (NSF International)  ·  See testing standards ›

Ingredients: Coenzyme Q-10 (Ubiquinone), Cellulose (vegetable capsule), Rice Flour.

Science behind this product

CoQ10 and Antioxidant Markers

In a meta-analysis of 17 randomised trials (972 participants), CoQ10 raised blood levels of total antioxidant capacity and superoxide dismutase and lowered malondialdehyde compared with placebo. The authors advised that the results be taken with caution because research was limited. These are laboratory markers, not health outcomes. Source

CoQ10 and Statin Medicines

Statins lower blood CoQ10: across 8 placebo-controlled treatment arms, plasma CoQ10 fell by 0.44 µmol/L, and the authors noted that the clinical relevance is unclear. Source For statin muscle symptoms, a meta-analysis of 6 randomised trials (302 patients) found no significant benefit of CoQ10, Source and a 2020 meta-analysis of 7 trials (321 patients) did not find benefit for muscle pain or for staying on the statin. Source A small trial of 32 patients reported lower pain scores with CoQ10 100 mg/day, with no change in the vitamin E comparison group, Source whereas a trial of 600 mg/day ubiquinol in 41 people with confirmed statin muscle pain found no reduction in pain. Source

CoQ10 in Heart Failure and Blood Pressure Studies

In the Q-SYMBIO trial of 420 people with moderate to severe heart failure on standard therapy, CoQ10 300 mg/day was associated with fewer major cardiovascular events over 2 years (15% vs 26%), while 16-week endpoints did not change significantly. This result applies to people with heart failure, not to people who take CoQ10 for general health. Source A 2025 meta-analysis of 45 randomised trials found systolic blood pressure about 3.4 mmHg lower with CoQ10, with no significant effect on diastolic pressure or heart rate. Source

Manufacturer Country: USA | Product Amount: 30 caps | Gross Weight: 0.25lb (113g)

Suggested Use: Take one (1) capsule twice a day as a dietary supplement. For best results, take 20-30 min before a meal or as directed by your healthcare professional.

Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place. The Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.

Gluten-free Vegetarian Lactose-free Allergen-free Hormone-free All natural Corn-free Vegan friendly Sugar-free

Questions

Frequently Asked Questions